48 Hours in Quito: A Practical Layover Guide

Spend your first 24 hours acclimatizing in the UNESCO-listed Old Town and the second 24 hours visiting the Middle of the World and the local highlands. Stay in the Mariscal or Centro Histórico districts to keep transit times to under 30 minutes.

  1. Handle your arrival. Quito's airport (UIO) is 45 minutes to an hour from the city. Do not take street taxis; use the official airport taxi stand or book a private transfer through your accommodation for a flat rate of $25-$30.
  2. Prioritize altitude safety. Quito sits at 2,850 meters (9,350 feet). Drink double the water you think you need, skip alcohol on your first night, and take it slow to avoid altitude sickness before your Galápagos flight.
  3. Navigate the city. Use Uber for short hops within the city—it is cheap ($2-$5) and safer than hailing cabs. For longer distances, stick to registered hotel shuttles or private drivers.
Is it safe to walk around the Old Town at night?
Stick to the main tourist thoroughfares like Calle La Ronda or the areas around Plaza Grande. Avoid dark alleyways and always use an Uber after dark.
Should I exchange money in Quito?
Ecuador uses the US Dollar. Bring small denominations ($1, $5, $10). Finding change for $50 or $100 bills can be difficult in smaller shops.